Return to Our Home Page
   
   

Pulmonary Emphysema

What is pulmonary emphysema?

Chronic Obstructive Pulmonary Disease (COPD)

COPD is a term that refers to a large group of lung diseases which can interfere with normal breathing. It is estimated that 11 percent of the US population has COPD. The two most common conditions of COPD are chronic bronchitis and emphysema.

The causes of COPD are not fully understood. It is generally agreed that the most important cause of chronic bronchitis and emphysema is cigarette smoking. Causes such as air pollution and occupational exposures may play a role, especially when combined with cigarette smoking. Heredity also plays a contributing role in some patients' emphysema, and is especially important in a rare form -- due to alpha 1-antitrypsin deficiency.

Symptoms
Patients with chronic bronchitis usually have cough and sputum for many years before they develop shortness of breath.

Patients with emphysema usually have shortness of breath and develop cough and sputum during a respiratory infection, or in the later stages of the illness.

Emphysema is a chronic lung condition in which alveoli, or air sacs, may be:

  • destroyed

  • narrowed

  • collapsed

  • stretched

  • over-inflated

Over-inflation of the air-sacs is a result of a breakdown of the walls of the alveoli, and causes a decrease in respiratory function and breathlessness. Damage to the air sacs is irreversible and results in permanent "holes" in the tissues of the lower lungs.

What are the symptoms of pulmonary emphysema?
The following are the most common symptoms for pulmonary emphysema, however, each person may experience symptoms differently.

Early symptoms of pulmonary emphysema may include:

  • shortness of breath

  • cough

Other symptoms may include:

  • fatigue

  • anxiety

  • sleep problems

  • heart problems

  • weight loss

  • depression

The symptoms of pulmonary emphysema may resemble other lung conditions or medical problems. Consult your physician for a diagnosis.

What are the causes of pulmonary emphysema?
Emphysema does not develop suddenly, but occurs very gradually. The lung has a system of elastic fibers that allow the lungs to expand and contract. Pulmonary emphysema occurs when a breakdown in the chemical balance that protects the lungs against the destruction of the elastic fibers occurs.

There are a number of reasons for the breakdown in chemical balance:

  • smoking

  • exposure to air pollution

  • irritating fumes and dusts on the job

  • a rare inherited form of the disease called alpha 1-antitrypsin (AAT) deficiency-related pulmonary emphysema, or early onset pulmonary emphysema

How is pulmonary emphysema diagnosed?
In addition to a complete medical history and physical examination, the physician may request the following:

  • pulmonary function tests - to determine characteristics and capabilities of the lungs

  • spirometry - to measure the amount of air that can be forced out

  • peak flow meter - to evaluate changes in breathing and response to medications

  • blood tests - to analyze the amount of carbon dioxide and oxygen in the blood

  • chest x-ray

  • sputum analysis - to examine the mucus for infection

  • electrocardiogram (ECG or EKG) - to measure the electrical activity of the heart

Treatment for pulmonary emphysema:
Specific treatment will be determined by your doctor(s) based on:

  • your age, overall health, and medical history

  • extent of the disease

  • your tolerance for specific medications, procedures or therapies

  • expectations for the course of the disease

  • your opinion or preference

The goal of treatment for people with pulmonary emphysema is to live more comfortably with the disease by providing relief of symptoms and preventing progression of the disease with a minimum of side effects. Treatment may include:

  • quitting smoking - the single most important factor for maintaining healthy lungs

  • antibiotics for bacterial infections

  • oral medications

  • bronchodilators and other inhaled medications

  • exercise -- including breathing exercises to strengthen the muscles used in breathing as part of a pulmonary rehabilitation program to condition the rest of the body

  • oxygen supplementation from portable containers

  • lung reduction surgery to remove damaged area of the lung

  • lung transplantation

This content was last reviewed by a University of Maryland Medicine expert on May 16, 2003